Health-Related Quality of Life in Parkinson's Disease after Pallidotomy and Deep Brain Stimulation
Identifieur interne : 003173 ( Main/Corpus ); précédent : 003172; suivant : 003174Health-Related Quality of Life in Parkinson's Disease after Pallidotomy and Deep Brain Stimulation
Auteurs : Kristy Straits-Tröster ; Julie A. Fields ; Steven B. Wilkinson ; Rajesh Pahwa ; Kelly E. Lyons ; William C. Koller ; Alexander I. TrösterSource :
- Brain and Cognition [ 0278-2626 ] ; 2000.
Abstract
This study explored the multidimensional outcome of three neurosurgical interventions for Parkinson's disease (PD): pallidotomy (N = 23), pallidal deep brain stimulation (DBS) (N = 9), and thalamic DBS (N = 7). All patients completed the Sickness Impact Profile (SIP) and the Beck Depression Inventory. Pallidotomy patients also completed the Profile of Mood States, the Beck Anxiety Inventory, and a disease-specific quality of life (QOL) measure, the Parkinson's Disease Questionnaire (PDQ-39). Three months after surgery, all neurosurgical groups showed significant improvements in mood and function, including physical, psychosocial, and overall functioning. Pallidal DBS and pallidotomy patients who completed additional QOL measures reported decreased anxiety and tension, increased vigor, improved mobility and ability to perform activities of daily living, and decreased perceived stigma. Psychosocial dysfunction scores from the SIP were related to depressed mood both at baseline (r = .42) and at followup (r = .45), but the physical dysfunction subscale was not related to mood at either time point, suggesting that disruption of social relationships due to PD may have more impact on affective distress than physical symptoms alone. Results suggest that neurosurgical interventions for PD improve disabling PD motor symptoms and also improve several domains of quality of life.
Url:
DOI: 10.1006/brcg.1999.1112
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Health-Related Quality of Life in Parkinson's Disease after Pallidotomy and Deep Brain Stimulation</title><author><name sortKey="Straits Troster, Kristy" sort="Straits Troster, Kristy" uniqKey="Straits Troster K" first="Kristy" last="Straits-Tröster">Kristy Straits-Tröster</name><affiliation><mods:affiliation>Department of Veterans Affairs Medical Center</mods:affiliation></affiliation></author><author><name sortKey="Fields, Julie A" sort="Fields, Julie A" uniqKey="Fields J" first="Julie A." last="Fields">Julie A. Fields</name><affiliation><mods:affiliation>Department of Neurology, University of Kansas Medical Center</mods:affiliation></affiliation></author><author><name sortKey="Wilkinson, Steven B" sort="Wilkinson, Steven B" uniqKey="Wilkinson S" first="Steven B." last="Wilkinson">Steven B. Wilkinson</name><affiliation><mods:affiliation>Division of Neurosurgery, University of Kansas Medical Center</mods:affiliation></affiliation></author><author><name sortKey="Pahwa, Rajesh" sort="Pahwa, Rajesh" uniqKey="Pahwa R" first="Rajesh" last="Pahwa">Rajesh Pahwa</name><affiliation><mods:affiliation>Department of Neurology, University of Kansas Medical Center</mods:affiliation></affiliation></author><author><name sortKey="Lyons, Kelly E" sort="Lyons, Kelly E" uniqKey="Lyons K" first="Kelly E." last="Lyons">Kelly E. Lyons</name><affiliation><mods:affiliation>Department of Neurology, University of Kansas Medical Center</mods:affiliation></affiliation></author><author><name sortKey="Koller, William C" sort="Koller, William C" uniqKey="Koller W" first="William C." last="Koller">William C. 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Tröster</name><affiliation><mods:affiliation>Department of Neurology, University of Kansas Medical Center</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Brain and Cognition</title><title level="j" type="abbrev">YBRCG</title><idno type="ISSN">0278-2626</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2000">2000</date><biblScope unit="volume">42</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="399">399</biblScope><biblScope unit="page" to="416">416</biblScope></imprint><idno type="ISSN">0278-2626</idno></series><idno type="istex">7A19A84F0B1525B170E7D709E749EEF32169EDD1</idno><idno type="DOI">10.1006/brcg.1999.1112</idno><idno type="PII">S0278-2626(99)91112-0</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0278-2626</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">This study explored the multidimensional outcome of three neurosurgical interventions for Parkinson's disease (PD): pallidotomy (N = 23), pallidal deep brain stimulation (DBS) (N = 9), and thalamic DBS (N = 7). All patients completed the Sickness Impact Profile (SIP) and the Beck Depression Inventory. Pallidotomy patients also completed the Profile of Mood States, the Beck Anxiety Inventory, and a disease-specific quality of life (QOL) measure, the Parkinson's Disease Questionnaire (PDQ-39). Three months after surgery, all neurosurgical groups showed significant improvements in mood and function, including physical, psychosocial, and overall functioning. Pallidal DBS and pallidotomy patients who completed additional QOL measures reported decreased anxiety and tension, increased vigor, improved mobility and ability to perform activities of daily living, and decreased perceived stigma. Psychosocial dysfunction scores from the SIP were related to depressed mood both at baseline (r = .42) and at followup (r = .45), but the physical dysfunction subscale was not related to mood at either time point, suggesting that disruption of social relationships due to PD may have more impact on affective distress than physical symptoms alone. Results suggest that neurosurgical interventions for PD improve disabling PD motor symptoms and also improve several domains of quality of life.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>Kristy Straits-Tröster</name><affiliations><json:string>Department of Veterans Affairs Medical Center</json:string></affiliations></json:item><json:item><name>Julie A. Fields</name><affiliations><json:string>Department of Neurology, University of Kansas Medical Center</json:string></affiliations></json:item><json:item><name>Steven B. Wilkinson</name><affiliations><json:string>Division of Neurosurgery, University of Kansas Medical Center</json:string></affiliations></json:item><json:item><name>Rajesh Pahwa</name><affiliations><json:string>Department of Neurology, University of Kansas Medical Center</json:string></affiliations></json:item><json:item><name>Kelly E. Lyons</name><affiliations><json:string>Department of Neurology, University of Kansas Medical Center</json:string></affiliations></json:item><json:item><name>William C. Koller</name><affiliations><json:string>Department of Neurology, University of Kansas Medical Center</json:string></affiliations></json:item><json:item><name>Alexander I. Tröster</name><affiliations><json:string>Department of Neurology, University of Kansas Medical Center</json:string></affiliations></json:item></author><language><json:string>eng</json:string></language><abstract>This study explored the multidimensional outcome of three neurosurgical interventions for Parkinson's disease (PD): pallidotomy (N = 23), pallidal deep brain stimulation (DBS) (N = 9), and thalamic DBS (N = 7). All patients completed the Sickness Impact Profile (SIP) and the Beck Depression Inventory. Pallidotomy patients also completed the Profile of Mood States, the Beck Anxiety Inventory, and a disease-specific quality of life (QOL) measure, the Parkinson's Disease Questionnaire (PDQ-39). Three months after surgery, all neurosurgical groups showed significant improvements in mood and function, including physical, psychosocial, and overall functioning. Pallidal DBS and pallidotomy patients who completed additional QOL measures reported decreased anxiety and tension, increased vigor, improved mobility and ability to perform activities of daily living, and decreased perceived stigma. Psychosocial dysfunction scores from the SIP were related to depressed mood both at baseline (r = .42) and at followup (r = .45), but the physical dysfunction subscale was not related to mood at either time point, suggesting that disruption of social relationships due to PD may have more impact on affective distress than physical symptoms alone. 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We appreciate the help of Jennifer Kieltyka for assistance with patient recruitment and evaluation and acknowledge the courage and commitment of our participants.</note><note>Address correspondence and reprint requests to Kristy Straits-Tröster, DVAMC Kansas City, 4801 E. Linwood Blvd. (116-B), Kansas City, MO 64128. Fax: (816) 861-1110. E-mail: troster@kansas-city.va.gov.</note><note type="content">Section title: Regular Article</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Health-Related Quality of Life in Parkinson's Disease after Pallidotomy and Deep Brain Stimulation</title><author><persName><forename type="first">Kristy</forename><surname>Straits-Tröster</surname></persName><affiliation>Department of Veterans Affairs Medical Center</affiliation></author><author><persName><forename type="first">Julie A.</forename><surname>Fields</surname></persName><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation></author><author><persName><forename type="first">Steven B.</forename><surname>Wilkinson</surname></persName><affiliation>Division of Neurosurgery, University of Kansas Medical Center</affiliation></author><author><persName><forename type="first">Rajesh</forename><surname>Pahwa</surname></persName><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation></author><author><persName><forename type="first">Kelly E.</forename><surname>Lyons</surname></persName><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation></author><author><persName><forename type="first">William C.</forename><surname>Koller</surname></persName><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation></author><author><persName><forename type="first">Alexander I.</forename><surname>Tröster</surname></persName><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation></author></analytic><monogr><title level="j">Brain and Cognition</title><title level="j" type="abbrev">YBRCG</title><idno type="pISSN">0278-2626</idno><idno type="PII">S0278-2626(00)X0012-7</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="2000"></date><biblScope unit="volume">42</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="399">399</biblScope><biblScope unit="page" to="416">416</biblScope></imprint></monogr><idno type="istex">7A19A84F0B1525B170E7D709E749EEF32169EDD1</idno><idno type="DOI">10.1006/brcg.1999.1112</idno><idno type="PII">S0278-2626(99)91112-0</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2000</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>This study explored the multidimensional outcome of three neurosurgical interventions for Parkinson's disease (PD): pallidotomy (N = 23), pallidal deep brain stimulation (DBS) (N = 9), and thalamic DBS (N = 7). All patients completed the Sickness Impact Profile (SIP) and the Beck Depression Inventory. Pallidotomy patients also completed the Profile of Mood States, the Beck Anxiety Inventory, and a disease-specific quality of life (QOL) measure, the Parkinson's Disease Questionnaire (PDQ-39). Three months after surgery, all neurosurgical groups showed significant improvements in mood and function, including physical, psychosocial, and overall functioning. Pallidal DBS and pallidotomy patients who completed additional QOL measures reported decreased anxiety and tension, increased vigor, improved mobility and ability to perform activities of daily living, and decreased perceived stigma. Psychosocial dysfunction scores from the SIP were related to depressed mood both at baseline (r = .42) and at followup (r = .45), but the physical dysfunction subscale was not related to mood at either time point, suggesting that disruption of social relationships due to PD may have more impact on affective distress than physical symptoms alone. Results suggest that neurosurgical interventions for PD improve disabling PD motor symptoms and also improve several domains of quality of life.</p></abstract></profileDesc><revisionDesc><change when="2000">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/7A19A84F0B1525B170E7D709E749EEF32169EDD1/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla" xml:lang="en"><item-info><jid>YBRCG</jid><aid>91112</aid><ce:pii>S0278-2626(99)91112-0</ce:pii><ce:doi>10.1006/brcg.1999.1112</ce:doi><ce:copyright type="full-transfer" year="2000">Academic Press</ce:copyright></item-info><head><ce:article-footnote><ce:label>☆</ce:label><ce:note-para>Portions of this study were presented at the Twenty-Sixth Annual International Neuropsychological Society Meeting, in Honolulu, Hawaii, and the Nineteenth Annual Meeting of the Society of Behavioral Medicine, in New Orleans, Louisiana. We appreciate the help of Jennifer Kieltyka for assistance with patient recruitment and evaluation and acknowledge the courage and commitment of our participants.</ce:note-para><ce:note-para>Address correspondence and reprint requests to Kristy Straits-Tröster, DVAMC Kansas City, 4801 E. Linwood Blvd. (116-B), Kansas City, MO 64128. Fax: (816) 861-1110. E-mail: troster@kansas-city.va.gov.</ce:note-para></ce:article-footnote><ce:dochead><ce:textfn>Regular Article</ce:textfn></ce:dochead><ce:title>Health-Related Quality of Life in Parkinson's Disease after Pallidotomy and Deep Brain Stimulation</ce:title><ce:author-group><ce:author><ce:given-name>Kristy</ce:given-name><ce:surname>Straits-Tröster</ce:surname><ce:cross-ref refid="A1"><ce:sup>a</ce:sup></ce:cross-ref><ce:cross-ref refid="A2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Julie A.</ce:given-name><ce:surname>Fields</ce:surname><ce:cross-ref refid="A2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Steven B.</ce:given-name><ce:surname>Wilkinson</ce:surname><ce:cross-ref refid="A3"><ce:sup>c</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Rajesh</ce:given-name><ce:surname>Pahwa</ce:surname><ce:cross-ref refid="A2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Kelly E.</ce:given-name><ce:surname>Lyons</ce:surname><ce:cross-ref refid="A2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>William C.</ce:given-name><ce:surname>Koller</ce:surname><ce:cross-ref refid="A2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>Alexander I.</ce:given-name><ce:surname>Tröster</ce:surname><ce:cross-ref refid="A2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="A1"><ce:label>a</ce:label><ce:textfn>Department of Veterans Affairs Medical Center</ce:textfn></ce:affiliation><ce:affiliation id="A2"><ce:label>b</ce:label><ce:textfn>Department of Neurology, University of Kansas Medical Center</ce:textfn></ce:affiliation><ce:affiliation id="A3"><ce:label>c</ce:label><ce:textfn>Division of Neurosurgery, University of Kansas Medical Center</ce:textfn></ce:affiliation></ce:author-group><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>This study explored the multidimensional outcome of three neurosurgical interventions for Parkinson's disease (PD): pallidotomy (<ce:italic>N</ce:italic> = 23), pallidal deep brain stimulation (DBS) (<ce:italic>N</ce:italic> = 9), and thalamic DBS (<ce:italic>N</ce:italic> = 7). All patients completed the Sickness Impact Profile (SIP) and the Beck Depression Inventory. Pallidotomy patients also completed the Profile of Mood States, the Beck Anxiety Inventory, and a disease-specific quality of life (QOL) measure, the Parkinson's Disease Questionnaire (PDQ-39). Three months after surgery, all neurosurgical groups showed significant improvements in mood and function, including physical, psychosocial, and overall functioning. Pallidal DBS and pallidotomy patients who completed additional QOL measures reported decreased anxiety and tension, increased vigor, improved mobility and ability to perform activities of daily living, and decreased perceived stigma. Psychosocial dysfunction scores from the SIP were related to depressed mood both at baseline (<ce:italic>r</ce:italic> = .42) and at followup (<ce:italic>r</ce:italic> = .45), but the physical dysfunction subscale was not related to mood at either time point, suggesting that disruption of social relationships due to PD may have more impact on affective distress than physical symptoms alone. Results suggest that neurosurgical interventions for PD improve disabling PD motor symptoms and also improve several domains of quality of life.</ce:simple-para></ce:abstract-sec></ce:abstract></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Health-Related Quality of Life in Parkinson's Disease after Pallidotomy and Deep Brain Stimulation</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Health-Related Quality of Life in Parkinson's Disease after Pallidotomy and Deep Brain Stimulation</title></titleInfo><name type="personal"><namePart type="given">Kristy</namePart><namePart type="family">Straits-Tröster</namePart><affiliation>Department of Veterans Affairs Medical Center</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Julie A.</namePart><namePart type="family">Fields</namePart><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Steven B.</namePart><namePart type="family">Wilkinson</namePart><affiliation>Division of Neurosurgery, University of Kansas Medical Center</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Rajesh</namePart><namePart type="family">Pahwa</namePart><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Kelly E.</namePart><namePart type="family">Lyons</namePart><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">William C.</namePart><namePart type="family">Koller</namePart><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Alexander I.</namePart><namePart type="family">Tröster</namePart><affiliation>Department of Neurology, University of Kansas Medical Center</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">2000</dateIssued><copyrightDate encoding="w3cdtf">2000</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">This study explored the multidimensional outcome of three neurosurgical interventions for Parkinson's disease (PD): pallidotomy (N = 23), pallidal deep brain stimulation (DBS) (N = 9), and thalamic DBS (N = 7). All patients completed the Sickness Impact Profile (SIP) and the Beck Depression Inventory. Pallidotomy patients also completed the Profile of Mood States, the Beck Anxiety Inventory, and a disease-specific quality of life (QOL) measure, the Parkinson's Disease Questionnaire (PDQ-39). Three months after surgery, all neurosurgical groups showed significant improvements in mood and function, including physical, psychosocial, and overall functioning. Pallidal DBS and pallidotomy patients who completed additional QOL measures reported decreased anxiety and tension, increased vigor, improved mobility and ability to perform activities of daily living, and decreased perceived stigma. Psychosocial dysfunction scores from the SIP were related to depressed mood both at baseline (r = .42) and at followup (r = .45), but the physical dysfunction subscale was not related to mood at either time point, suggesting that disruption of social relationships due to PD may have more impact on affective distress than physical symptoms alone. Results suggest that neurosurgical interventions for PD improve disabling PD motor symptoms and also improve several domains of quality of life.</abstract><note>Portions of this study were presented at the Twenty-Sixth Annual International Neuropsychological Society Meeting, in Honolulu, Hawaii, and the Nineteenth Annual Meeting of the Society of Behavioral Medicine, in New Orleans, Louisiana. We appreciate the help of Jennifer Kieltyka for assistance with patient recruitment and evaluation and acknowledge the courage and commitment of our participants.</note><note>Address correspondence and reprint requests to Kristy Straits-Tröster, DVAMC Kansas City, 4801 E. Linwood Blvd. (116-B), Kansas City, MO 64128. Fax: (816) 861-1110. E-mail: troster@kansas-city.va.gov.</note><note type="content">Section title: Regular Article</note><relatedItem type="host"><titleInfo><title>Brain and Cognition</title></titleInfo><titleInfo type="abbreviated"><title>YBRCG</title></titleInfo><genre type="Journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">200004</dateIssued></originInfo><identifier type="ISSN">0278-2626</identifier><identifier type="PII">S0278-2626(00)X0012-7</identifier><part><date>200004</date><detail type="volume"><number>42</number><caption>vol.</caption></detail><detail type="issue"><number>3</number><caption>no.</caption></detail><extent unit="issue pages"><start>309</start><end>438</end></extent><extent unit="pages"><start>399</start><end>416</end></extent></part></relatedItem><identifier type="istex">7A19A84F0B1525B170E7D709E749EEF32169EDD1</identifier><identifier type="DOI">10.1006/brcg.1999.1112</identifier><identifier type="PII">S0278-2626(99)91112-0</identifier><accessCondition type="use and reproduction" contentType="">© 2000Academic Press</accessCondition><recordInfo><recordContentSource>ELSEVIER</recordContentSource><recordOrigin>Academic Press, ©2000</recordOrigin></recordInfo></mods></metadata><enrichments><istex:catWosTEI uri="https://api.istex.fr/document/7A19A84F0B1525B170E7D709E749EEF32169EDD1/enrichments/catWos"><teiHeader><profileDesc><textClass><classCode scheme="WOS">PSYCHOLOGY, EXPERIMENTAL</classCode><classCode scheme="WOS">NEUROSCIENCES</classCode></textClass></profileDesc></teiHeader></istex:catWosTEI></enrichments><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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